Giuseppe Nicola Nasini (1657–1736) was an Italian painter of the Baroque period.
Born in Siena, he was one of the Tuscan pupils in the Medici-patronized Grand-Ducal Academy for the Arts located in Rome and directed from 1673-86, by Ciro Ferri. Nasini returned to Florence by 1685. During the reign of Cosimo III de' Medici, Nasini and Giuseppe Tonelli were commissioned to fresco an Allegory of the moral and religious virtues of the Medici for ceiling of the gallery of the Uffizi that overlooks the river Arno. In 1720, he returned to Rome, where he painted in the church of the Santi Apostoli, the Quirinal Palace, and one of the nave paintings in San Giovanni in Laterano. In Foligno, he painted a San Leonardo for the church of the Madonna del Pianto. In the Chapel of the Madonna inside the church of Santa Maria della Scala in Siena, he painted, along with his son Apollonio, a series of paintings consisting of large canvases portraying scenes from the life of the Virgin, including:Birth of the Virgin, Presentation in the Temple, and Flight into Egypt, as well as frescoes depicting the Coronation of the Virgin and the Virgin crowned by the Trinity with angels upholding instruments of the Passion.